Use cases

Start from a familiar R&D situation.

Each route connects a scientific or industrial objective to relevant academic capabilities and next steps.

Microscopy and preclinical evaluation in a laboratory setting.

Typical project routes

From objective to offer.

Validate a gene therapy target.
Use case

Validate a gene therapy target

A biotech team needs to strengthen the biological rationale before committing to vector or delivery development.

R&D need
Target discovery, preclinical validation, biomarkers
Possible route
Review related categories, open matching offers, then connect with the relevant expert team if the project crosses several domains.
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Access a preclinical retinal model.
Use case

Access a preclinical retinal model

An ophthalmology program needs relevant retinal models, imaging and functional assessment routes.

R&D need
Retinal models, imaging, ophthalmology platforms
Possible route
Review related categories, open matching offers, then connect with the relevant expert team if the project crosses several domains.
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Prepare GMP and pre-GMP bioproduction.
Use case

Prepare GMP / pre-GMP bioproduction

A project team needs to move from proof of concept toward reproducible process, batch and QC readiness.

R&D need
Pre-GMP, GMP, CMC, biotesting
Possible route
Review related categories, open matching offers, then connect with the relevant expert team if the project crosses several domains.
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Build clinical and real-world evidence.
Use case

Build clinical and real-world evidence

A company approaching clinical development needs trial expertise, patient data and long-term follow-up routes.

R&D need
Clinical validation, registries, RWE
Possible route
Review related categories, open matching offers, then connect with the relevant expert team if the project crosses several domains.
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Explore organoids and organ-on-chip models.
Use case

Explore organoids / organ-on-chip

A program needs human-relevant models to test safety, efficacy or mechanism in a translational setting.

R&D need
Organoids, organ-on-chip, platforms
Possible route
Review related categories, open matching offers, then connect with the relevant expert team if the project crosses several domains.
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Identify biomarkers and monitoring tools.
Use case

Identify biomarkers and monitoring tools

A team needs measurable response, progression or safety markers across development stages.

R&D need
Biomarkers, imaging, monitoring
Possible route
Review related categories, open matching offers, then connect with the relevant expert team if the project crosses several domains.
View related offers

Next step

Explore the related offers or ask the alliance team to guide you.

From research to application

Curie Cancer

The EpCART Program

The EpCART program is a flagship example of CellAction’s capabilities in translating cutting-edge science into clinical innovation.

Explore the offer and full use case

I2C

API-FLOW-CRIST: continuous-flow synthesis and crystallization of ibuprofen

CARMeN and SMS laboratories at Carnot i2C demonstrated the feasibility of coupling continuous-flow synthesis and crystallization of ibuprofen and its sodium salt, Na-Ibu, to optimize and intensify pharmaceutical processes.

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I2C

High-resolution mass spectrometry imaging

The MALDI-FTICR imaging approach developed by CARMeN at Carnot i2C can locate and quantify anticancer molecules such as carboplatin and temozolomide, and contrast agents such as Dotarem, in biological tissues, including mouse and pig brain sections.

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I2C

Biomaterials for regeneration and tissue engineering

Carnot i2C develops bioinspired heterogeneous macromolecular scaffolds for tissue regeneration, controlling the three-dimensional architecture of biomaterials.

Explore the offer and full use case