Improve Efficiency, Stability and Applications of Adoptive T Cell Therapy

Strengthen efficacy and safety evidence using relevant preclinical models and translational data.

Scientific visual associated with Improve Efficiency, Stability and Applications of Adoptive T Cell Therapy
Biomarkers expertise — Curie Cancer
01Carnot instituteCurie Cancer
02Development stagePreclinical validation
03Main expertiseBiomarkers
04Relevant fieldsOncology

Offer overview

What this offer helps you achieve

Strengthen efficacy and safety evidence using relevant preclinical models and translational data.

Scientific and technical scope

Our technology enhances CAR-T cell therapy for solid tumors by overcoming their immunosuppressive environment. SOCS1 inactivation in CD4+ and CD8+ T cells boosts intratumor accumulation, proliferation, survival, and functionality, promoting tumor rejection. This results in more effective, durable CAR-T therapies and enables the production of functional off-the-shelf allogenic cells.
01

Capabilities mobilised

Therapeutic areasValidation using preclinical modelsBiomarkers
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Application fields

Oncology

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Could this capability strengthen your R&D programme?

Present your scientific, technical or clinical need and identify the most relevant route to collaboration.